NGF and Alzheimer disease: The fact that microglia is a target cell of NGF in the brain (Rizzi et al., 2018) and that is a primary target of intranasal hNGFp in the 5xFAD Alzheimer’s model (Capsoni et al., 2017) suggests that the microglia-mediated broad neuroprotective actions of hNGFp might be exploited in other disease states, in addition to AD.