Eight inflammatory mediators were present at significantly (FDR adjusted p < 0.05) higher levels in the samples from patients with RA, including TWEAK/TNFSF12, IL-35, IFN-α2, pentraxin-3, gp130/sIL6Rb, sIL-6Ra, IL-19, and sTNF-R1. The gene discussed is IL19; the disease is rheumatoid arthritis.