After adjustment for traditional risk factors, heterozygote (CG) and homozygote (CC) genotypes of CDKAL1 rs7747752 were all associated with increased risk of GDM with ORs being 1.95 (95% CI: 1.15-3.31) and 3.07 (95% CI: 1.59-5.95), respectively. The gene discussed is CDKAL1; the disease is gestational diabetes.