TRPC1 and hydrops fetalis: At the later gestation time point the concentration of SM 34:1 for TRPC1 -/- -NF-L was 64% of that observed for the corresponding WT-NF-L arm, however TRPC1 -/- -HF-M and TRPC1 -/- -HF-L had SM 34:1 concentrations that were 230% and 160% greater than in the corresponding WT groups (Figure 5B).