Also, upon TGF-β1 stimulation, cardiac hypertrophy associated protein phospholipase C (PLC) and epithelial cell adhesion molecule (Ep-CAM), involved in epithelial-mesenchymal transition (EMT), showed a trend toward increased expression (p = 0.054 and p = 0.061, respectively). The gene discussed is HSPG2; the disease is cardiac hypertrophy.