CEACAM5 and Cowden disease: Therefore, in comparison with AIEC strains present in CD patients, which mostly adhere to human enterocytes via the interaction between type 1 fimbriae FimH adhesin and the CEACAM6 receptor (55), this study reveals that AIEC strains present in UC patients may use Dr fimbriae to adhere colonic enterocytes via the interaction with human receptors increased in UC such as CEACAM5.