JMJD6 is highly expressed in oral squamous cell carcinoma (OSCC), head and neck squamous cell carcinoma (HNSCC), esophageal squamous cell carcinoma (ESCC), osteosarcoma, acute myeloid leukemia (AML), and renal cell carcinoma (RCC). Here, JMJD6 is linked to osteosarcoma.