JMJD6 and neoplasm: For instance, JMJD6 was directly bound by Mir-770 targeting of its 3’-untranslated region (UTR), and acted as an oncogene in non-small cell lung cancer (NSCLC) cells, whereas overexpression of Mir-770 blocked tumor growth of NSCLC in vitro and in vivo via inhibiting JMJD6 and the WNT/β-catenin pathway (40).