CXCL13 and neoplasm: Injection of KrasG12D-PDEC or KPC derived cell lines into wild-type pancreas, in fact, typically leads to the accumulation of B-lymphocytes in close proximity to evolving tumor lesions, probably as a consequence of the secretion of the B-cell chemotactic molecule CXCL13 by stromal cells in the context of the growing pancreatic neoplasia (66).