CXCL3 and acute kidney injury: ↑Expression of CXCL3→↑ PRINS expression→Leading to AKI which is exacerbated graft rejection.Anti-CXCL3 → ↓PRINS → ↓ CD3+ T cell infiltration on day 7 post-TX→ ↓Creatinine and BUN level → Improved renal function.