Previously, studies have shown that HOTAIR polymorphisms remarkably enhance the risk of different types of cancers [49], preeclampsia [50], primary ovarian insufficiency [51], coronary artery disease [52], etc. In contrast, Bayram et al. reported that HOTAIR rs920778 C/T polymorphisms were not associated with gastric cancer risk in a Turkish population [53]. The gene discussed is HOTAIR; the disease is preeclampsia.