HAMP and dentin dysplasia: In DD-CKD patients (Holdstock et al., 2016; Meadowcroft et al., 2019; Akizawa et al., 2020; Singh et al., 2021b), daprodustat significantly increased TSAT, TIBC and the total iron compared with rhEPO, but hepcidin and ferritin levels were not obviously changed.