As traditional Chinese medicine has attracted increasing attention, studies have illustrated that some herbal extracts have antifibrotic effects by suppressing the inflammation and oxidative stress induced by cytokines such as IL-6 and TGF-β1 (Wang et al., 2020; Wang Z. et al., 2021), but few of these medicines have been proven effective in clinical IPF patients. The gene discussed is TGFB1; the disease is idiopathic pulmonary fibrosis.