Enhanced Glut-1 protein as well as COX-2 (cyclooxygenase-2) is reported as one of the major driving factors, leading to the initiation and progress of PCa (Carreño et al., 2019; Gasinska et al., 2020; King et al., 2020; Joshi et al., 2021). The gene discussed is PTGS2; the disease is posterior cortical atrophy.