POU2AF1 and myeloid sarcoma: To evaluate possible correlations between the NTZ-associated modulation of Spi-B and POU2AF1 expression and miR-126-3p and sVCAM-1 serum concentration, with the presence/lack of JCPyV reactivation, we divided patients into “JCPyV uninfected” and “JCPyV infected” individuals; JCPyV infected individuals were further divided into patients with “JCPyV latency” or with “JCPyV activity.” For each MS subject, the virological characterization is summarized in Supplementary Figure S1.