TAC1 and colitis: The activation of TRPA1 can lead to the release of inflammatory tachykinins, such as substance P and neurokinin A, and calcitonin gene related peptide (CGRP), which has been shown to be protective in the dextran sodium sulfate (DSS)-induced colitis model as well as in UC patients (López-Requena et al., 2017; Utsumi et al., 2018).