Indeed, the LHb has been implicated in anhedonia (Li et al., 2013), learned helplessness (Li B. et al., 2011), and rumination (Belzung et al., 2015) which have all been linked to hopeless depression and suicidality in past literature (Abramson et al., 2000). The gene discussed is LHB; the disease is depressive symptom measurement.