Cheng et al. (2018) confirmed that NEAT1_2 detected a threefold increase in the brains of HD patients. Besides, it has been proved that NEAT1 is overexpressed of in HD model brain of transgenic mice (Chanda et al., 2018). Moreover, the roles of NEAT1 were also demonstrated in cell models of HD (Sunwoo et al., 2017). Here, NEAT1 is linked to Huntington disease.