UCA1 and Parkinson disease: Lu M. et al. (2018) explored that UCA1 promoted the expression of a-synuclein in PD development. Besides, Cai et al. (2019) showed that UCA1 could aggravate dopaminergic neuronal damage, inflammation, and oxidative stress by promoting the PI3K/Akt axis, while reduction of UCA1 exerted opposite effects in a PD rat model.