KCNC4 and Alzheimer disease: Although we did not replicate publishedfindings (Angulo et al.,2004) showing increased Kv3.4 levels in human AD brain comparedto controls, we do observe Kv3.4 specifically localised to synapses in humaniPSC-derived cortical neurons, supporting the possibility that Kv3.4 inhuman synapses may mediate Aβ-induced synaptotoxicity.