VIM and cancer: In this context, vimentin is localized to discrete cytoplasmic and membrane compartments (Figure 1) in mesenchymal cells (Mendez et al., 2010), fibroblasts (Mendez et al., 2010; Helfand et al., 2011; Ding et al., 2020), astrocytes (Lepekhin et al., 2001), epithelial cells (Vuoriluoto et al., 2011), cells in lymphoid tissues (Otsuki et al., 2011), glandular cells (Peuhu et al., 2017), and various cancer cell types (Vuoriluoto et al., 2011; Havel et al., 2015; Rawla et al., 2019; Kuppe et al., 2021; Thalla et al., 2021).