Notably, FAP expression was positively related to TMB in adenoid cystic carcinoma (ACC), thymoma, sarcoma, prostate adenocarcinoma, ovarian cancer (OV), acute myeloid leukemia, kidney chromophobe (KICH), and COAD, and negatively correlated with pancreatic adenocarcinoma (PAAD), LUSC, LIHC, HNSC, and kidney renal papillary cell carcinoma (KIRP). The gene discussed is FAP; the disease is prostate adenocarcinoma.