From the main DEGs, some were assigned as RNAs, miRNAs-regulated and those associated with cancer and neurodegenerative diseases, i.e., FAM135A, MTRNR2L2, PSD3, HMGA2, LIN7A, and MYH7B; as well as circRNAs i.e., ANKRD12 (recruitment of histone deacetylases), APC (involved in tumorigenesis), and PSD3 (associated with obesity, type 2 diabetes, and cholesterologenesis), and MTRNR2L10; from the lncRNA type, KTN1 (an anti-sense RNA involved in tumorigenesis and EMT). The gene discussed is FAM135A; the disease is obesity due to melanocortin 4 receptor deficiency.