Melanogenesis-related proteins (MRPs) including tyrosinase, TRP-1, TRP-2, gp100, and MART-1 are classified as major histocompatibility complex (MHC)-restricted tumor antigens, and specific peptides derived from processing of MRPs can activate T-lymphocyte responses against melanoma cells (175–180). This evidence concerns the gene MRPS7 and neoplasm.