IL-15Ra, IL-6, MIP-1a, CXCL10, and CSF-1, as well as oncostatin-M, TNFRSF9, PD-L1, CDCP1, and HGF, were those notably upregulated in both FS and LGLL, further emphasizing the link between cytokine and STAT3 dysregulation and disease pathogenesis (50). The gene discussed is CXCL10; the disease is T-cell large granular lymphocyte leukemia.