As shown, the protein levels of RhoA, YAP and Prox1 were notably increased, and the phosphorylated YAP (p-YAP) levels were reduced in the two lymphatic metastatic GC cells and their exosome-treated AGS cells compared to the corresponding controls (Figures 5A, B and Supplementary Figures 1H, I). Here, RHOA is linked to gastric cancer.