Firstly, we found that the levels of TMEM100 were higher in androgen receptor (AR)-positive PCa cell lines (LNCaP and 22RV1) than that of AR-negative cell lines (PC-3 and DU145, Figure 1), thus we speculate that AR signaling may play a role in TMEM100/GATA5 interaction in PCa. The gene discussed is GATA5; the disease is posterior cortical atrophy.