These genes were among others involved in cell adhesion (eg, NCAM1, ITGA6, and SDC1), tumor suppression (eg, PTEN, TUSC2, and TAGLN2), proliferation (eg, MKI67, MCM2, and CENPM), RNA splicing (eg, SRSF10, SF3A2, and PUF60), cell migration (eg, ROCK1, DOCK11, and DLC1), and DNA damage control (eg, CHEK1, DCLRE1C, and SLFN11; Data Supplement [Supplementary Table 4]).52-66. The gene discussed is CHEK1; the disease is neoplasm.