Although there are some previous studies on the role of cytokines in the development of long-term diabetes complications, there is little information about the immunological response and fluctuation of cytokine levels during the metabolic crisis of DKA.[20] Since this patient had T1DM, we think that her IL-6 and TNF-a levels were elevated at the onset of DKA. The gene discussed is IL6; the disease is diabetes mellitus.