This state of hyperinflammation is related to the ability of SARS-CoV-1, due to the expression of specific proteins, has to inhibit the production of type I interferon through the inhibition of the toll-like receptor 3 signaling pathways and toll-like receptor 7, for example,[39-41] which is fundamental in the host’s innate response against viral infections. The gene discussed is TLR7; the disease is viral infectious disease.