Several studies have shown the clinical significance of NLR and PRL in predicting the prognosis of pancreas ductal adenocarcinoma,[9,21] as well as other solid tumors.[10,11,22] In a metaanalysis that assessed the prognostic ability of NLR on overall survival in patients with pancreatic cancer,[23] a high preoperative NLR was identified to be associated with a poorer prognosis than that of patients with lower NLR values, with the cut-off values ranging from 2 to 5. The gene discussed is PRL; the disease is familial pancreatic carcinoma.