Tissue microarray‐based study of both node‐negative and node‐positive breast tumors showed that overexpression of phospho‐STAT3 (Tyr705) improved the short‐term survival and long‐term survival of patients with breast tumor, which indicated a better prognosis of patients with STAT3 positive breast cancer.52, 53. This evidence concerns the gene STAT3 and breast neoplasm.