Jiang et al. confirmed that B4GALNT1 promoted the progression and metastasis of lung adenocarcinoma through the JNK/c-Jun/Slug signalling pathway and was involved in the tumour development of melanoma and clear cell renal cell carcinoma (Yoshida, et al., 2020; Jiang, et al., 2021; Yang, et al., 2019). This evidence concerns the gene MAPK8 and melanoma.