EGFR and glioblastoma: POMGNT1 has been examined in depth in glioblastoma (GBM), and it can promote proliferation and invasion by regulating EGFR/ERK signalling (Lan, et al., 2015); Furthermore, it induces temozolomide resistance of tumour cells in GBM by regulating the expression of factors in EMT signalling (Liu, et al., 2017b).