INS and cardiovascular disorder: Taking the occurrence of CVD as the dependent variable and age, insulin use, FPG, TC, HbA1c, and HGI levels as the dependent variables, the multivariate logistic regression analysis showed that higher HGI level (OR = 4.660), older age (OR = 4.815), and higher FPG levels (OR = 1.717) were independent risk factors for cardiovascular disease in T2DM patients (P < 0.05), as shown in Table 3.