In all, there were 47 intersection targets obtained between SC and secondary malignant neoplasm of lung and 8 of them were regarded as hub targets after utilizing MCODE plug-in unit of Cytoscape, namely RELA, JUN, MAPK1, MAPK14, STAT3, IL-4, ESR1, and TP53. The gene discussed is MAPK1; the disease is lung cancer.