APOE and dementia: However, after adjusting for age, sex, APOE ε4 carriage, and baseline MoCA score, minor allele carrier status of rs68006382 was associated with accelerated conversion to MCI (HR = 1.973, 95% CI = 1.246–3.123, p = 0.004; Figure 2A), but not dementia (HR = 1.512, 95% CI = 0.753–3.034, p = 0.245).