In fact, hKLK7 overexpression induces the production of CD146 (cluster of differentiation 146) (79), also known as melanoma cell adhesion molecule (MCAM), a surface glycoprotein that functions as a receptor for laminin subunit alpha 4, a matrix protein expressed in vascular walls, which could be related to melanoma metastasis (80). The gene discussed is LAMA4; the disease is melanoma.