RNF170 and abscess: However, Nuc-mediated degradation of NETs and DNA released from dying host cells will certainly foster the accumulation of all four canonical deoxyribonucleotides within pyogenic abscesses and purulent exudates, raising the question of whether S. aureus may systematically generate a mixture of AdsA-derived effector deoxyribonucleosides to manipulate host nucleotide homeostasis modules and cell death machineries.