RNF170 and abscess: Moreover, these effects correlated with the expression of adsA suggesting that synchronous and AdsA-dependent biogenesis of dGuo and dAdo by S. aureus, along with dual targeting of the purine salvage pathway-apoptosis axis, boosts cell death of phagocytes in DNA- or deoxyribonucleotide-rich host environments such as abscesses (Figures 5D, E).