Concurrently, the advanced biochemical properties of AdsA could help the pathogen to secure the continued biogenesis of at least one cytotoxic deoxyribonucleoside during infection as the complex microenvironment of abscesses and infectious foci along with the variable GC-content of mammalian DNA fragments may locally restrict access of AdsA to appropriate and sufficient substrates. Here, RNF170 is linked to abscess.