Results showed the occurrence of colitis in SD mice, including weight loss (Figure S1A), colon shortening (Figures S1B, C), fecal occult blood (Figure S1F), the increase of histological score (Figures S1D, E), intestinal permeability (Figure S1G), and IL-17 levels (Figure S1H), compared with CON group. This evidence concerns the gene IL17A and colitis.