TNF and colitis: In contrast, MT and TAK-242 supplementation reversed the LPS-induced changes in colitis and the inflammatory response; no significant difference was showed in body weight (P > 0.052), colonic length (P > 0.556), colonic permeability (P > 0.345), histopathological score (P > 0.643), proinflammatory cytokines (TNF-α and IL-1β, P > 0.772), or anti-inflammatory factors (IL-10 and IFN-γ, P > 0.558) among the LPS+MT, LPS+NAC, LPS+TAK-242, and CON groups.