In this study, we investigated the expression of CB1R in lung fibroblasts isolated from BLM-challenged mice and found that CB1R mRNA levels were significantly increased in the isolated lung fibroblasts from mice with BLM-induced pulmonary fibrosis compared with control mice (Figure 3A), which is in accordance with the increased CB1R mRNA levels in lung tissues of pulmonary fibrosis mice (Figure 1A). The gene discussed is CNR1; the disease is pulmonary fibrosis.