Of note, Notch1, Notch2 and Notch3 are strongly overexpressed in the lung tissues of rats with ovalbumin‐induced asthma, and Notch1 inhibition by emodin treatment confers more remarkable transformations within the lung tissue than does Notch2 and Notch3 inhibition.26 The gene discussed is NOTCH1; the disease is asthma.