HBA2 and hemoglobinopathy: These findings are of clinical significance because 5 of the 10 β thalassemia heterozygotes with HbA2 between 3.0–3.2% and MCV > 80 fL and 2 of the 10 β thalassemia heterozygotes with HbA2 between 3.3–3.4% and MCV > 80 fL were married to carriers of a hemoglobinopathy.