In the development cohort, the proportions of progression to severe pneumonia in each category were seen as follows: age [< 50 years (0.7%), 50–59 years (6.0%), 60–69 years (10.3%), 70–79 years (17.6%), ≥ 80 years (37.5%)], hemoglobin [< 13 g/L (7.5%), ≥ 13 g/L (11.3%)], CRP [< 1.4 mg/dL (4.0%), ≥ 1.4 mg/dL (26.1%)], LDH [< 500 U/L (3.9%), 500–700 U/L (15.1%), ≥ 700 U/L (45.8%)]. This evidence concerns the gene CRP and pneumonia.