Among the T-ALL clusters, T-CLC1, T-CLC2, and T-CLC3 were composed of cortical DP cell lines or cell lines with unclear immunotyping, and T-CLC5, T-CLC6, and T-CLC7 contained the DN precursor cell lines (Supplementary Fig. 3e, f). Here, CLCN3 is linked to acute lymphoblastic leukemia.