INF2 and hemolytic-uremic syndrome: Currently, aHUS is classified as Streptococcus pneumoniae-HUS, influenza-HUS, alternative complement pathway dysregulation-HUS, complement-independent HUS (Cobalamin C, DGKE or INF2 mutation), HUS with coexisting disease (transplantation, autoimmune disorders, drugs, malignant hypertension, malignancy/cancer chemotherapy), and idiopathic HUS (unclear aetiology) [3, 4].