Compared with the si-PD-1 group, TGF-β secretion in tumor tissues was greatly declined to 70.0 pg/mL in the si-PD-1 + si-TGF-β group (*p < 0.05 vs. si-NC, **p < 0.01 vs. si-NC, ##p < 0.01 vs. si-PD-1). Here, TGFB1 is linked to neoplasm.