ZEB1 and neoplasm: Lee and his team tested the results of ferroptosis inducers induction in HNC cell lines or EMT inhibition and rat neoplasm graft models, found that overexpression of ZEB1 may enhance the neoplasm cells sensitivity to ferroptosis, and it absolutely was additionally confirmed in animal models that the neoplasm volume within the overexpression group was considerably reduced compared with the control group [29].