The results showed that in HF group the cardiac infarction area (Figure 8A, 8B), SOAT1 protein expression level (Figure 8C, 8D), ROS production and LDH activity in rat heart tissue homogenate (Figure 8E, 8F, 8O), BNP mRNA (Figure 8M) and the secretion of serum BNP (Figure 8N), inflammatory factors IL-1β and TNF-α (Figure 8G, 8H) were increased, and the expression level of DNMT3B protein (Figure 8C, 8D) in rat heart tissues and the systolic (Figure 8L), diastolic and mean arterial pressure of rats were decreased compared with the sham operation group (Figure 8J, 8K). Here, SOAT1 is linked to hydrops fetalis.