Of 60 samples obtained from 51 BC patients, 36 showed the expression of Cobll1/PACSIN2/SH3BP1 in two major patterns, Cobll1+/SH3BP1+ (13/36), and Cobll1+/PACSIN2+/SH3BP1+ (16/36); however, the other 24 BC samples and all 36 CP samples showed no expression of any of these proteins (Figure 6C), suggesting that expression of both Cobll1 and SH3BP1 is linked to BC progression. This evidence concerns the gene SH3BP1 and breast cancer.