Indeed, HSP90AA1 is the gene coding for HSP90 alpha, the stress-inducible isoform of HSP90 belonging to the family of molecular chaperones that have a key role in the stabilization of oncogenic proteins, such as Raf-1, ErbB2, Akt, and mutant p53, thus promoting survival of cancer cells [34]. The gene discussed is TP53; the disease is cancer.