CXCL8 and neoplasm: Based on our results, AM9928 inhibited the secretion of tumor-inflammatory molecules IL-6 and IL-8 and the angiogenic factor VEGF-A in MDA-MB-231 cells and MDA-MB-BrM2 cells (Fig. 3) as well as the murine GFP-4T1-BrM5 cells (Fig. 4a).