MGLL and neoplasm: Since AM9928 inhibited tumor growth in the mammary fat pads (Fig. 4) and prevented changes in BBB integrity in vivo, resulting in reduced tumor cell colonization in brain, we conclude that MAGL plays a role in TNBC tumor growth and TNBC transmigration across the BBB, in addition to its roles in neurological and neurodegenerative diseases25,26.