APOE and hypertensive disorder: In contrast, lower plasma Aβ42/Aβ40 (Fig. 4H, βstd = 0.097[95% CI, 0.009, 0.184], p = 0.030), higher FBP SUVR (Fig. 4I, βstd = −0.104 [95% CI, −0.193, −0.016], p = 0.021) and HTN (Fig. 4K, βstd = −0.304 [95% CI, −0.477, −0.132], p < 0.001) but not greater WMH (Fig. 4J) and lower BMI (Fig. 4L) at baseline predicted faster PACC decline (Fig.4F, G, I) in APOE-ε4 carriers.